SPAVATO - KETAMINE TREATMENT

If you’ve been diagnosed with treatment-resistant depression and are exploring new treatment options, SPRAVATO® may offer a path forward. Hudson Specialty Care Spravato in Cliffside Park, Elizabeth, Edison, New Jersey, and New York City, Manhattan and Brooklyn provides safe, in-office administration of this FDA-approved esketamine nasal spray for adults with treatment-resistant depression. While our team does not offer therapy or ongoing psychiatric care, we work closely with you and your existing mental health provider to deliver and monitor SPRAVATO® treatment in a comfortable, supportive setting. To learn more, call the office or schedule an appointment online today.

What is SPRAVATO®?

SPRAVATO® is a prescription nasal spray containing esketamine, approved by the FDA to help reduce symptoms of major depressive disorder (MDD) with suicidal thoughts or behaviors, as well as treatment-resistant depression (TRD). Unlike many antidepressants that can take weeks to work, SPRAVATO® can produce rapid symptom relief—often within 24 hours—making it a valuable option for those who haven’t found success with other treatments.

What conditions does SPRAVATO® address?

Hudson Specialty Care Spravato focuses exclusively on administering SPRAVATO® for:

• Treatment-resistant depression (TRD): For patients who have tried at least two antidepressants without adequate results.
• Major depressive disorder with suicidal thoughts or behaviors: If you’re in crisis, call 988 or seek immediate medical help. Once you’re safe, SPRAVATO® may be considered as part of your ongoing care plan.

How does SPRAVATO® work?

Esketamine, the active ingredient in SPRAVATO®, targets NMDA receptors in the brain, which are linked to mood regulation. This unique mechanism is different from traditional antidepressants and can help restore neural connections that may be damaged by long-term depression. Many patients report feeling relief within hours, which can help them re-engage in daily activities and therapy more effectively.

What should I expect with SPRAVATO® treatment?

Your first step is an evaluation to confirm your eligibility for SPRAVATO®. If prescribed by your mental health provider, our team will coordinate your treatment schedule and ensure all safety protocols are followed. We also provide a comfortable, quiet environment for each session, with staff available to answer questions and help you feel at ease.

During each visit, you’ll self-administer the nasal spray under medical supervision. We’ll monitor you for about two hours afterward to assess your response and check for side effects, which may include dizziness, dissociation, anxiety, or sleepiness. Because of these possible effects, you’ll need a safe ride home and should plan to rest after your appointment.

SPRAVATO® treatments are typically given twice weekly for the first month, with frequency tapering in later phases. Many patients notice gradual improvements over time, especially when SPRAVATO® is combined with ongoing mental health support from their regular provider.

At Hudson Specialty Care Spravato, we focus on making your treatment sessions safe, consistent, and supportive so you can move toward lasting relief. To learn more, call the office or request an appointment online.